Publications

2024

Michael L. Lipton. A Promise to Keep, but Miles to Go Before We Sleep. Journal of Pharmacology and Experimental Therapeutics May 1, 2024, 389 (2) 133-135; DOI: https://doi.org/10.1124/jpet.123.001939.

2023

Charney MF, Ye KQ, Fleysher R, DeMessie B, Stewart WF, Zimmerman ME, Kim M, Lipton RB, Lipton ML. Age of first exposure to soccer heading: Associations with cognitive, clinical, and imaging outcomes in the Einstein Soccer Study. Front Neurol. 2023 Feb 9;14:1042707. doi: 10.3389/fneur.2023.1042707. PMID: 36846112; PMCID: PMC9947556.

Hoogenboom WS, Rubin TG, Ambadipudi K, Cui MH, Ye K, Foster H, Elkouby E, Liu J, Branch CA, Lipton ML. Evolving brain and behaviour changes in rats following repetitive subconcussive head impacts. Brain Commun. 2023 Nov 20;5(6):fcad316. doi: 10.1093/braincomms/fcad316. PMID: 38046094; PMCID: PMC10691880.

2022

Song JY, Patton CD, Friedman R, Mahajan LS, Nordlicht R, Sayed R, Lipton ML. Hormonal contraceptives and the brain: A systematic review on 60 years of neuroimaging, EEG, and biochemical studies in humans and animals. Front Neuroendocrinol. 2023 Jan;68:101051. doi: 10.1016/j.yfrne.2022.101051. Epub 2022 Dec 25. PMID: 36577486; PMCID: PMC9898167.

Ye K, Fleysher R, Lipton RB, Zimmerman ME, Stewart WF, Sliwinski MJ, Kim M, Lipton ML. Repetitive soccer heading adversely impacts short-term learning among adult women. J Sci Med Sport. 2022 Nov;25(11):935-941. doi: 10.1016/j.jsams.2022.08.011. Epub 2022 Aug 26. PMID: 36210312; PMCID: PMC10020927.

2021

Liu J, Lin C, Minuti A, Lipton M. Arterial spin labeling compared to dynamic susceptibility contrast MR perfusion imaging for assessment of ischemic penumbra: A systematic review. J Neuroimaging. 2021 Nov;31(6):1067-1076. doi: 10.1111/jon.12913. Epub 2021 Aug 13. PMID: 34388271.

Ivanovic V, Seiler S, Tarraf W, Crivello E, Martinez O, Lipton RB, Isasi CR, Copello TG, Talavera GA, Gallo LC, Lamar M, Testai F, Schneiderman N, Gellman MD, Daviglus M, Gonzalez HM, DeCarli C, Lipton ML. Prevalence of incidental brain MRI findings of clinical relevance in a diverse Hispanic/Latino population. J Neuroimaging. 2021 Nov;31(6):1166-1175. doi: 10.1111/jon.12910. Epub 2021 Jul 19. PMID: 34288226; PMCID: PMC10332335.

Chen KX, Worley S, Foster H, Edasery D, Roknsharifi S, Ifrah C, Lipton ML. Oral contraceptive use is associated with smaller hypothalamic and pituitary gland volumes in healthy women: A structural MRI study. PLoS One. 2021 Apr 21;16(4):e0249482. doi: 10.1371/journal.pone.0249482. PMID: 33882080; PMCID: PMC8059834.

Gil N, Lipton ML, Fleysher R. Registration quality filtering improves robustness of voxel-wise analyses to the choice of brain template. Neuroimage. 2021 Feb 15;227:117657. doi: 10.1016/j.neuroimage.2020.117657. Epub 2020 Dec 15. PMID: 33338620; PMCID: PMC7880909.

2020

Sandmo SB, Gooijers J, Seer C, Kaufmann D, Bahr R, Pasternak O, Lipton ML, Tripodis Y, Koerte IK. Evaluating the validity of self-report as a method for quantifying heading exposure in male youth soccer. Res Sports Med. 2021 Sep-Oct;29(5):427-439. doi: 10.1080/15438627.2020.1853541. Epub 2020 Dec 6. PMID: 33283535.

Strauss SB, Fleysher R, Ifrah C, Hunter LE, Ye K, Lipton RB, Zimmerman ME, Kim M, Stewart WF, Lipton ML. Framing potential for adverse effects of repetitive subconcussive impacts in soccer in the context of athlete and non-athlete controls. Brain Imaging Behav. 2021 Apr;15(2):882-895. doi: 10.1007/s11682-020-00297-4. PMID: 32712797; PMCID: PMC7861653.

Oliveira TG, Ifrah C, Fleysher R, Stockman M, Lipton ML. Soccer heading and concussion are not associated with reduced brain volume or cortical thickness. PLoS One. 2020 Aug 10;15(8):e0235609. doi: 10.1371/journal.pone.0235609. PMID: 32776940; PMCID: PMC7416951.

Levitch CF, McConathey E, Aghvinian M, Himmelstein M, Lipton ML, Zimmerman ME. The Impact of Sleep on the Relationship between Soccer Heading Exposure and Neuropsychological Function in College-Age Soccer Players. J Int Neuropsychol Soc. 2020 Aug;26(7):633-644. doi: 10.1017/S1355617720000211. Epub 2020 Feb 26. PMID: 32098640.

Hunter LE, Freudenberg-Hua Y, Davies P, Kim M, Lipton RB, Stewart WF, Srinivasan P, Hu S, Lipton ML. Associations of Apolipoprotein E ε4 Genotype and Ball Heading With Verbal Memory in Amateur Soccer Players. JAMA Neurol. 2020 Apr 1;77(4):419-426. doi: 10.1001/jamaneurol.2019.4828. PMID: 31985774; PMCID: PMC6990972.

Cunqueiro A, Lipton ML, Dym RJ, Jain VR, Sterman J, Scheinfeld MH. Re: performing MRI on patients with MRI-conditional and non-conditional cardiac implantable electronic devices: an update for radiologists. A reply. Clin Radiol. 2020 May;75(5):390-391. doi: 10.1016/j.crad.2020.02.007. Epub 2020 Mar 12. PMID: 32172945.

2019

Sterman J, Cunqueiro A, Dym RJ, Spektor M, Lipton ML, Revzin MV, Scheinfeld MH. Implantable Electronic Stimulation Devices from Head to Sacrum: Imaging Features and Functions. Radiographics. 2019 Jul-Aug;39(4):1056-1074. doi: 10.1148/rg.2019180088. PMID: 31283461.

Hunter LE, Lubin N, Glassman NR, Xue X, Spira M, Lipton ML. Comparing Region of Interest versus Voxel-Wise Diffusion Tensor Imaging Analytic Methods in Mild and Moderate Traumatic Brain Injury: A Systematic Review and Meta-Analysis. J Neurotrauma. 2019 Apr 15;36(8):1222-1230. doi: 10.1089/neu.2018.5838. Epub 2018 Dec 19. PMID: 30375271; PMCID: PMC6479248. 

Hunter LE, Freudenberg-Hua Y, Davies P, Kim M, Fleysher R, Stewart WF, Lipton RB, Lipton ML. BDNF Val⁶⁶Met Positive Players Demonstrate Diffusion Tensor Imaging Consistent With Impaired Myelination Associated With High Levels of Soccer Heading: Indication of a Potential Gene-Environment Interaction Mechanism. Front Neurol. 2019 Dec 11;10:1297. doi: 10.3389/fneur.2019.01297. PMID: 31920921; PMCID: PMC6918922.

Hunter LE, Branch CA, Lipton ML. The neurobiological effects of repetitive head impacts in collision sports. Neurobiol Dis. 2019 Mar;123:122-126. doi: 10.1016/j.nbd.2018.06.016. Epub 2018 Jun 21. PMID: 29936233; PMCID: PMC6453577.

Hoogenboom WS, Rubin TG, Ye K, Cui MH, Branch KC, Liu J, Branch CA, Lipton ML. Diffusion Tensor Imaging of the Evolving Response to Mild Traumatic Brain Injury in Rats. J Exp Neurosci. 2019 Jul 5;13:1179069519858627. doi: 10.1177/1179069519858627. PMID: 31308735; PMCID: PMC6613065.

Hoogenboom WS, Branch CA, Lipton ML. Animal models of closed-skull, repetitive mild traumatic brain injury. Pharmacol Ther. 2019 Jun;198:109-122. doi: 10.1016/j.pharmthera.2019.02.016. Epub 2019 Feb 26. PMID: 30822463; PMCID: PMC6536340.

Ezzati A, Zammit AR, Lipton ML, Lipton RB. The relationship between hippocampal volume, chronic pain, and depressive symptoms in older adults. Psychiatry Res Neuroimaging. 2019 Jul 30;289:10-12. doi: 10.1016/j.pscychresns.2019.05.003. Epub 2019 May 15. PMID: 31112826; PMCID: PMC6645699.

Cunqueiro A, Lipton ML, Dym RJ, Jain VR, Sterman J, Scheinfeld MH. Performing MRI on patients with MRI-conditional and non-conditional cardiac implantable electronic devices: an update for radiologists. Clin Radiol. 2019 Dec;74(12):912-917. doi: 10.1016/j.crad.2019.07.006. Epub 2019 Aug 17. PMID: 31431253.

2018

Tan K, Meiri A, Mowrey WB, Abbott R, Goodrich JT, Sandler AL, Suri AK, Lipton ML, Wagshul ME. Diffusion tensor imaging and ventricle volume quantification in patients with chronic shunt-treated hydrocephalus: a matched case-control study. J Neurosurg. 2018 Dec 1;129(6):1611-1622. doi: 10.3171/2017.6.JNS162784. PMID: 29350598. 

Suri AK, Lipton ML. Neuroimaging of brain trauma in sports. Handb Clin Neurol. 2018;158:205-216. doi: 10.1016/B978-0-444-63954-7.00021-5. PMID: 30482348.

Rubin TG, Catenaccio E, Fleysher R, Hunter LE, Lubin N, Stewart WF, Kim M, Lipton RB, Lipton ML. MRI-defined White Matter Microstructural Alteration Associated with Soccer Heading Is More Extensive in Women than Men. Radiology. 2018 Nov;289(2):478-486. doi: 10.1148/radiol.2018180217. Epub 2018 Jul 31. PMID: 30063172; PMCID: PMC6209057.

McClelland AC, Fleysher R, Mu W, Kim N, Lipton ML. White matter microstructural abnormalities in blast-exposed combat veterans: accounting for potential pre-injury factors using consanguineous controls. Neuroradiology. 2018 Oct;60(10):1019-1033. doi: 10.1007/s00234-018-2070-9. Epub 2018 Aug 17. PMID: 30116841.

Levitch CF, Ifrah C, Kim M, Stewart WF, Lipton RB, Zimmerman ME, Lipton ML. Personality and Risk Taking in Sports: A Focus on Unintentional and Intentional Head Impacts in Amateur Soccer Players. Clin J Sport Med. 2020 Sep;30(5):484-488. doi: 10.1097/JSM.0000000000000627. PMID: 29933278; PMCID: PMC6309518.

Hunter LE, Ifrah C, Zimmerman ME, Kim M, Lipton RB, Stewart WF, Lipton ML. Heading and unintentional head impacts have opposing associations with Patient Reported Outcomes in amateur soccer players. Res Sports Med. 2018 Oct-Dec;26(4):390-400. doi: 10.1080/15438627.2018.1492396. Epub 2018 Jul 13. PMID: 30003822; PMCID: PMC6387588. 

Goldman-Yassen AE, Chen KX, Edasery D, Hsu K, Ye K, Lipton ML. Near-Term Decrease in Brain Volume following Mild Traumatic Injury Is Detectible in the Context of Preinjury Volumetric Stability: Neurobiologic Insights from Analysis of Historical Imaging Examinations. AJNR Am J Neuroradiol. 2018 Oct;39(10):1821-1826. doi: 10.3174/ajnr.A5769. Epub 2018 Sep 6. PMID: 30190258; PMCID: PMC7410747. 

Fleysher R, Lipton ML, Noskin O, Rundek T, Lipton R, Derby CA. White matter structural integrity and transcranial Doppler blood flow pulsatility in normal aging. Magn Reson Imaging. 2018 Apr;47:97-102. doi: 10.1016/j.mri.2017.11.003. Epub 2017 Nov 21. PMID: 29158187; PMCID: PMC5828865. 

Fay JS, Milch HS, Gutman D, Law AS, Mardakhaev E, Saraiya MS, Lipton ML. MR. Implant: Rapid Evidence-Based Determination of Implant Safety Status. J Am Coll Radiol. 2018 Jul;15(7):993-997. doi: 10.1016/j.jacr.2018.02.029. Epub 2018 Apr 19. PMID: 29680405.

Broglio SP, Kontos AP, Levin H, Schneider K, Wilde EA, Cantu RC, Feddermann-Demont N, Fuller GW, Gagnon I, Gioia GA, Giza C, Griesbach GS, Leddy JJ, Lipton ML, Mayer AR, McAllister TW, McCrea M, McKenzie LB, Putukian M, Signoretti S, Suskauer SJ, Tamburro R, Turner M, Yeates KO, Zemek R, Ala’i S, Esterlitz J, Gay K, Bellgowan PSF, Joseph K. National Institute of Neurological Disorders and Stroke and Department of Defense Sport-Related Concussion Common Data Elements Version 1.0 Recommendations. J Neurotrauma. 2018 Dec 1;35(23):2776-2783. doi: 10.1089/neu.2018.5643. Epub 2018 Jul 23. PMID: 29717643; PMCID: PMC6247979.

Stewart WF, Kim N, Ifrah C, Sliwinski M, Zimmerman ME, Kim M, Lipton RB, Lipton ML. Heading Frequency Is More Strongly Related to Cognitive Performance Than Unintentional Head Impacts in Amateur Soccer Players. Front Neurol. 2018 Apr 24;9:240. doi: 10.3389/fneur.2018.00240. PMID: 29740384; PMCID: PMC5928847.

2017

2016

Catenaccio E, Caccese J, Wakschlag N, Fleysher R, Kim N, Kim M, Buckley TA, Stewart WF, Lipton RB, Kaminski T, Lipton ML. Validation and calibration of HeadCount, a self-report measure for quantifying heading exposure in soccer players. Res Sports Med. 2016 Oct-Dec;24(4):416-425. doi: 10.1080/15438627.2016.1234472. Epub 2016 Sep 22. PMID: 27788599; PMCID: PMC5144162.

Strauss SB, Kim N, Branch CA, Kahn ME, Kim M, Lipton RB, Provataris JM, Scholl HF, Zimmerman ME, Lipton ML. Bidirectional Changes in Anisotropy Are Associated with Outcomes in Mild Traumatic Brain Injury. AJNR Am J Neuroradiol. 2016 Nov;37(11):1983-1991. doi: 10.3174/ajnr.A4851. Epub 2016 Jun 9. PMID: 27282864; PMCID: PMC5148740.

Ezzati A, Katz MJ, Zammit AR, Lipton ML, Zimmerman ME, Sliwinski MJ, Lipton RB. Differential association of left and right hippocampal volumes with verbal episodic and spatial memory in older adults. Neuropsychologia. 2016 Dec;93(Pt B):380-385. doi: 10.1016/j.neuropsychologia.2016.08.016. Epub 2016 Aug 16. PMID: 27542320; PMCID: PMC5154822.

Zimmerman ME, Ezzati A, Katz MJ, Lipton ML, Brickman AM, Sliwinski MJ, Lipton RB. Perceived Stress Is Differentially Related to Hippocampal Subfield Volumes among Older Adults. PLoS One. 2016 May 4;11(5):e0154530. doi: 10.1371/journal.pone.0154530. PMID: 27144832; PMCID: PMC4856349.

Kim N, Heo M, Fleysher R, Branch CA, Lipton ML. Two step Gaussian mixture model approach to characterize white matter disease based on distributional changes. J Neurosci Methods. 2016 Sep 1;270:156-164. doi: 10.1016/j.jneumeth.2016.04.024. Epub 2016 Apr 29. PMID: 27139737; PMCID: PMC5683897.

Fink AZ, Mogil LB, Lipton ML. Advanced neuroimaging in the clinic: critical appraisal of the evidence base. Br J Radiol. 2016 Aug;89(1064):20150753. doi: 10.1259/bjr.20150753. Epub 2016 May 5. PMID: 27074623; PMCID: PMC5124868.

Catenaccio E, Mu W, Lipton ML. Estrogen- and progesterone-mediated structural neuroplasticity in women: evidence from neuroimaging. Brain Struct Funct. 2016 Nov;221(8):3845-3867. doi: 10.1007/s00429-016-1197-x. Epub 2016 Feb 20. PMID: 26897178; PMCID: PMC5679703.

2015 – 2004

Strauss S, Hulkower M, Gulko E, Zampolin RL, Gutman D, Chitkara M, Zughaft M, Lipton ML. Current Clinical Applications and Future Potential of Diffusion Tensor Imaging in Traumatic Brain Injury. Top Magn Reson Imaging. 2015 Dec;24(6):353-62. doi: 10.1097/RMR.0000000000000071. PMID: 26636640. 

Jaspan ON, Fleysher R, Lipton ML. Compressed sensing MRI: a review of the clinical literature. Br J Radiol. 2015;88(1056):20150487. doi: 10.1259/bjr.20150487. Epub 2015 Sep 24. PMID: 26402216; PMCID: PMC4984938. 

Suri AK, Fleysher R, Lipton ML. Subject Based Registration for Individualized Analysis of Diffusion Tensor MRI. PLoS One. 2015 Nov 18;10(11):e0142288. doi: 10.1371/journal.pone.0142288. PMID: 26580077; PMCID: PMC4651497.

Kim N, Heo M, Fleysher R, Branch CA, Lipton ML. A gaussian mixture model approach for estimating and comparing the shapes of distributions of neuroimaging data: diffusion-measured aging effects in brain white matter. Front Public Health. 2014 Apr 14;2:32. doi: 10.3389/fpubh.2014.00032. PMID: 24783191; PMCID: PMC3995036.

Lipton ML, Bigler ED. Clarifying the Robust Foundation for and Appropriate Use of DTI in mTBI Patients. AJOB Neurosci. 2014;5(2):41-43. doi: 10.1080/21507740.2014.884191. PMID: 25386384; PMCID: PMC4223772.

Lipton ML, Kim N, Zimmerman ME, Kim M, Stewart WF, Branch CA, Lipton RB. Soccer heading is associated with white matter microstructural and cognitive abnormalities. Radiology. 2013 Sep;268(3):850-7. doi: 10.1148/radiol.13130545. Epub 2013 Jun 11. PMID: 23757503; PMCID: PMC3750422.

Hulkower MB, Poliak DB, Rosenbaum SB, Zimmerman ME, Lipton ML. A decade of DTI in traumatic brain injury: 10 years and 100 articles later. AJNR Am J Neuroradiol. 2013 Nov-Dec;34(11):2064-74. doi: 10.3174/ajnr.A3395. Epub 2013 Jan 10. PMID: 23306011; PMCID: PMC7964847.

Sternberg EJ, Lipton ML, Burns J. Utility of diffusion tensor imaging in evaluation of the peritumoral region in patients with primary and metastatic brain tumors. AJNR Am J Neuroradiol. 2014 Mar;35(3):439-44. doi: 10.3174/ajnr.A3702. Epub 2013 Sep 19. PMID: 24052506; PMCID: PMC7964735.

Kim N, Branch CA, Kim M, Lipton ML. Whole brain approaches for identification of microstructural abnormalities in individual patients: comparison of techniques applied to mild traumatic brain injury. PLoS One. 2013;8(3):e59382. doi: 10.1371/journal.pone.0059382. Epub 2013 Mar 26. PMID: 23555665; PMCID: PMC3608654.

Hornstein A, Stidham K, Lichtman S, Seliger G, Quail B, Bragnaccio J, Lipton ML, Muldoon A, Gardin T, 4-Aminopyridine for Post-Concussion Symptoms, Journal of Neuropsychiatry and Clinical Neuroscience, 25(2):5 2013.

Lipton ML, Kim N, Park YK, Hulkower MB, Gardin TM, Shifteh K, Kim M, Zimmerman ME, Lipton RB, Branch CA. Robust detection of traumatic axonal injury in individual mild traumatic brain injury patients: intersubject variation, change over time and bidirectional changes in anisotropy. Brain Imaging Behav. 2012 Jun;6(2):329-42. doi: 10.1007/s11682-012-9175-2. PMID: 22684769.

Rosenbaum SB, Lipton ML. Embracing chaos: the scope and importance of clinical and pathological heterogeneity in mTBI. Brain Imaging Behav. 2012 Jun;6(2):255-82. doi: 10.1007/s11682-012-9162-7. PMID: 22549452.

Dym RJ, Burns J, Freeman K, Lipton ML. Is functional MR imaging assessment of hemispheric language dominance as good as the Wada test?: a meta-analysis. Radiology. 2011 Nov;261(2):446-55. doi: 10.1148/radiol.11101344. Epub 2011 Jul 29. PMID: 21803921.

Lipton ML, Gulko E, Zimmerman ME, Friedman BW, Kim M, Gellella E, Gold T, Shifteh K, Ardekani BA, Branch CA. Diffusion-tensor imaging implicates prefrontal axonal injury in executive function impairment following very mild traumatic brain injury. Radiology. 2009 Sep;252(3):816-24. doi: 10.1148/radiol.2523081584. Epub 2009 Jun 30. PMID: 19567646.

Lipton ML, Gellella E, Lo C, Gold T, Ardekani BA, Shifteh K, Bello JA, Branch CA. Multifocal white matter ultrastructural abnormalities in mild traumatic brain injury with cognitive disability: a voxel-wise analysis of diffusion tensor imaging. J Neurotrauma. 2008 Nov;25(11):1335-42. doi: 10.1089/neu.2008.0547. PMID: 19061376.

Gold MM, Lipton ML. Neurological picture. Diffusion tractography of axonal degeneration following shear injury. J Neurol Neurosurg Psychiatry. 2008 Dec;79(12):1374-5. doi: 10.1136/jnnp.2008.148759. PMID: 19010948.

Yarmish G, Lipton ML, Functional MRI: From Acquisition to Application, Einstein Journal of Biology and Medicine, 2004; 20(1): 2-9.

Lipton ML. Keeping it safe: MRI site design, operations, and surveillance at an extended university health system. J Am Coll Radiol. 2004 Oct;1(10):749-54. doi: 10.1016/j.jacr.2004.04.016. PMID: 17411695.